Red Bull KTM Tech 3
- Maverick Vinales (multi-tahunan)
- Enea Bastianini (multi-tahunan)

LCR Honda
- Johann Zarco (2025)
- Somkiat Chantra (2025)*

Trackhouse Racing
- Raul Fernandez (multi-tahunan)
- Ai Ogura (2026)*

Pertamina Enduro VR46 Racing Team
- Fabio di Giannantonio (2026)
- Franco Morbidelli (2025)

Gresini Racing
- Alex Marquez (2026)
- Fermin Aldeguer (2026)*

Prima Pramac Racing (Yamaha)
Rumor: Jack Miller, dan Miguel Oliveira

*) debutan/rookie